Here is an excerpt from research that is being conducted on mild-mod TBI in the VA (blast wound victims):

"The Interactive Metronome® (IM) is a neurotechnology medical device that uses the principles of neuroplasticity to encourage recovery of function and cortical integration. In a randomized, controlled study examining the effects of IM training on boys with attention deficit disorder, the control group (who received IM treatment) improved on a host of measures, including attention, motor control, language processing, reading, and parental reports of improvements in regulation of aggressive behavior. These symptoms are commonly seen in individuals surviving TBI.

Neuroplastic processes are regulated by several factors. These include: attentional modulation, patterning of sensory activation, timing of sensory inputs, duration of experience, pairing with neuromodulatory influences, the neurochemical environment, and correlation of sensory inputs. Traditional therapy interventions in rehabilitation address some of these key elements (i.e., prescription of a stimulant medication during TBI rehabilitation, which alters the neurochemical environment and assists with attentional modulation.) However, other key aspects of the neuroplastic process (i.e., patterning of sensory activation, timing of inputs, and correlation of sensory inputs with motor outputs) are vastly more difficult to standardize in traditional speech, occupational, and physical therapies.